Effectiveness of Regular Aerobic Exercise in Improving Vascular Stiffness in Elderly Korean Women

The purpose of this study was to determine the effects aerobic exercise on carotid femoral pulse wave velocity (cf-PWV), cell adhesion molecules (intracellular (ICAM-1), vascular (VCAM-1), endothelial selectin (E-selectin), and oxidized LDL in elderly women aged 70–85 years, identify effect correlation with stiffness. Forty participants were recruited divided into three groups; stiffness (VSG, n = 14), obesity (OG, normal (NG, 12). All groups given a 16-week intervention exercise, data collected before after analyzed using SPSS Ver. 23.0. Two-way repeated-measures ANOVA used evaluate between-group time-dependent interaction effects. One-way variations. In addition, significance tested post hoc test (Scheffe). within-group variations by time examined paired t-test, analysis performed Pearson coefficients. Simple regression for variables showing significant differences. results indicate cf-PWV (p < 0.001), VCAM-1 0.01), E-selectin 0.05), 0.001). rate change positively correlated that (r 0.352, p 0.05) 0.325, statistical significance. To VCAM-1, tested, coefficient determination 0.124, indicating 12.4% fit standard line. also 0.106, 10.6% Thus, regular consistent program had cf-PWV, ICAM-1, E-selectin, Korean stiffness, suggesting improvements based which is predicted contribute prevention dysfunction lowering risk cardiovascular disease due atherosclerosis, as well having positive impairment cells.